The last few blocks of IA 3 are getting a makeover today. Dubuque is converting a handful of streets that run east-west into two-way streets instead of one-ways, including 9th and 11th, which currently carry US 52 and IA 3 between the US 61/151 freeway and White and Central streets. KCRG and KWWL both have stories.
This should not, or at least doesn’t have to, change the signage of the highways in the area. The exit from US 61/151 is designed with the one-ways in mind. It’s not unheard of for a two-way street to carry only one direction of a road, just really rare. The change will eventually be a moot point for US 52 and IA 3 anyway, because they will no longer run there when the Southwest Connector is built. (Eventually. Very, very eventually.)